PATHOGENETIC BASIS OF IMPROVING THE DETOXIFICATION ABILITY OF THE BODY

Vlasov Alexey Petrovich, Doctor of medical sciences, professor, head of sub-department of faculty surgery, Mordovia State University named after N. P. Ogaryov (Saransk), vap.61@yandex.ru
Shibitov Vyacheslav Alexandrovich, Candidate of medical science, assistant, sub-department of faculty surgery, Mordovia State University named after N. P. Ogaryov (Saransk), vap.61@yandex.ru
Vlasova Tatyana Ivanovna, Candidate of medical science, assistant, sub-department of sociology, Mordovia State University named after N. P. Ogaryov (Saransk), vap.61@yandex.ru
Rakhmetullova Gusel Rashidovna, Postgraduate student, Mordovia State University named after N.P.Ogaryov(Saransk), vap.61@yandex.ru
Gashimova Selminas Kamilyevna, Postgraduate student, Mordovia State University named after N.P.Ogaryov (Saransk), vap.61@yandex.ru
Vasilyev Vladimir Vladimirovich, Postgraduate student, Mordovia State University named after N.P.Ogaryov (Saransk), vap.61@yandex.ru

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The authors have ascertained that the development of acute renal failure in the simulation of acute peritonitis is associated with changes in lipid metabolism and coagulationlytic system of kidney tissue structures. The basis of high nefroprotective effect of complex therapy is its ability to recover functional and metabolic state of kidneys rapidly and efficiently. The positive effect of the combination is also due to the decrease of coagulation potential and the increase of fibrinolytic activity of blood plasma and tissue structures of kidneys.

endogenous intoxication, kidneys, peritonitis, lipids, hemostasis, etoksidol, fraxiparine.